FDA-cleared profile

Salix Central

Artrya Limited

Salix Central is a web-based adjunctive tool for qualified professionals to view, post-process, and analyze cardiac CT DICOM images for physician-identified coronary plaque and stenosis assessment and non-contrast calcium scoring.

Evidence status: each field shows source quality, applicability, and review date. Research pending, information not established in reviewed sources, and vendor documentation pending are distinct outcomes.

Clinical fit

What this tool is for

Start with the authorized purpose, then verify how it fits your service line and reading workflow.

Exact purpose
Salix Central is a web-based adjunctive tool for qualified professionals to view, post-process, and analyze cardiac CT DICOM images for physician-identified coronary plaque and stenosis assessment and non-contrast calcium scoring.
FDA source Exact FDA submission Checked 2026-09-07
Intended users
Qualified healthcare professionals reviewing adult cardiac CT; the software is adjunctive and does not replace professional judgment.
FDA source Exact FDA submission Checked 2026-09-07
Care setting and population
Adult cardiac CT/CCTA interpretation in cardiology or radiology practice.
FDA source Exact FDA submission Checked 2026-09-07
Workflow role
Cardiac CT post-processing that supports coronary plaque and stenosis review, non-contrast calcium scoring, vessel measurements, and physician reporting.
FDA source Exact FDA submission Checked 2026-09-07
Required input
Cardiac CT DICOM images: contrast CCTA with physician-identified plaque or stenosis and non-contrast cardiac CT for calcium scoring.
FDA source Exact FDA submission Checked 2026-09-07
Output and human action
Calcium scoring; coronary centerline extraction; vessel labeling; lumen and vessel-wall segmentation; coronary measurements; and a standard coronary report for clinician review.
FDA source Exact FDA submission Checked 2026-09-07
Limitations
The software is adjunctive, requires qualified professional review, and does not replace clinical judgment. FDA validation was task-specific and regulatory; it does not establish independent clinical outcomes or performance for every scanner, protocol, or later family version.
FDA source Exact FDA submission Checked 2026-09-07

Regulatory identity

FDA record and catalog context

The FDA listing establishes the regulatory identity. It does not by itself establish local workflow fit, pricing, security, or performance in your environment.

FDA submission
K243038
FDA source Exact FDA submission Checked 2026-08-31
Modality
CT/CTA
FDA source Exact FDA submission Checked 2026-09-07
Anatomy
Heart/Cardiovascular
FDA source Exact FDA submission Checked 2026-09-07
Clearance type
510(k)
FDA source Exact FDA submission Checked 2026-08-31
Decision date
2025-03-27
FDA source Exact FDA submission Checked 2026-08-31
FDA status
FDA-cleared
FDA source Exact FDA submission Checked 2026-08-31

Implementation

Questions for IT, informatics, and operations

Use these fields to structure a vendor demo, security review, and implementation estimate.

Integration
The exact submission accepts cardiac CT DICOM images through a secured network server and stores images; local PACS/RIS routing, identifiers, report delivery, and retention require acceptance testing.
FDA source Exact FDA submission Checked 2026-09-07
Deployment and data flow
The FDA packet describes a web-based application using AWS cloud services and a secured network server; it does not establish current hosting region, retention, availability, service-level terms, or the exact deployed cloud configuration.
FDA source Exact FDA submission Checked 2026-09-07
Security and privacy
Not established in reviewed sources
Reviewed sources checked Exact FDA submission Checked 2026-09-07

The reviewed exact packet and Artrya family pages do not establish current scoped security controls, certification scope, PHI flow, retention, access control, audit, or incident response for K243038.

Training and support
Use requires qualified professional review of coronary measurements, segmentation, calcium scores, and reports; local onboarding should cover CCTA versus non-contrast inputs, editing, report review, and escalation.
FDA source Exact FDA submission Checked 2026-09-07
Monitoring and change control
Monitor image eligibility, plaque and stenosis identification, calcium and segmentation edits, report completeness, DICOM delivery, reader overrides, failed or repeated analyses, downtime, updates, complaints, and recalls by exact K243038 release.
FDA source Exact FDA submission Checked 2026-09-07

Buyer acceptance guidance derived from the exact FDA workflow and validation scope; it is not a claimed vendor monitoring service.

AWS-backed web workflow

The exact FDA submission describes a web-based application using AWS cloud services, secured network-server connectivity, and image storage; confirm the current hosting region, data boundary, retention, and service terms with the vendor.

exact submission · checked 2026-09-07

Artrya Salix family workflow

Artrya's current Salix indication describes a web-based tool for trained professionals that supports cardiac CT plaque, stenosis, and calcium scoring on CT data from any CT scanner as an adjunct to clinical judgment.

product family · checked 2026-09-07

Current family indication; confirm exact K243038 version, scanner compatibility, hosting, licensing, and local interfaces.

Current U.S. identity cross-check

Artrya's investor-relations page identifies Salix Central as the U.S. product cleared under K243038; it does not establish every current family feature or contract term for the cleared configuration.

exact submission · checked 2026-09-07

Evidence

Performance evidence

Metrics are shown only when they are tied to a source, endpoint, population, and tested product version.

Evidence summary
K243038 FDA evidence is a six-center regulatory validation of Salix Central cardiac CT post-processing; no independent paper or trial was promoted in this timeboxed review.
FDA source Exact FDA submission Checked 2026-09-07
Reported sensitivity
Research pending
Needs research Exact FDA submission Checked 2026-08-31

This field has not been curated yet.

Reported specificity
Research pending
Needs research Exact FDA submission Checked 2026-08-31

This field has not been curated yet.

Calcium score Pearson correlation

0.958 Pearson correlation coefficient

Agreement of calcium score with reference in 302 non-contrast cardiac CT studies in the validation dataset.

Tested version: Salix Central configuration described in K243038

Centerline true placement

90.4 percent

Correct coronary centerline placement in 116 contrast cardiac CT studies in the validation dataset.

Tested version: Salix Central configuration described in K243038

Lumen-wall segmentation Dice

0.8996 Dice similarity coefficient

Agreement of lumen-wall segmentation with reference in 63 contrast cardiac CT studies in the validation dataset.

Tested version: Salix Central configuration described in K243038

K243038 Salix Central regulatory validation

Retrospective multi-center regulatory validation of calcium scoring, coronary centerline and labeling, and lumen/vessel-wall segmentation against reference results. · 363 unique de-identified cardiac CT studies from six centers across three U.S. states; task-specific sets included 302 non-contrast and 116 contrast studies.

exact submission · Tested version: Salix Central configuration described in K243038 · n=363 · 6 sites · Sponsor or vendor study

K243038

Manufacturer-submitted FDA evidence; it is not an independent clinical-outcome study. The FDA summary's printed confidence interval for vessel-label F1 is internally malformed and was not promoted as a metric.

Economics and lifecycle

Budget and ongoing governance

These are common procurement questions; unknown values remain visible until a source supports them.

Pricing and total cost
Not established in reviewed sources
Reviewed sources checked Exact FDA submission Checked 2026-09-07

No public list price or contract unit for the exact K243038 configuration was established in the reviewed official sources.

Reimbursement and coding
Research pending
Needs research Exact FDA submission Checked 2026-09-07

CMS plaque-policy context was not applied to this dossier; no product-specific coverage determination is made.

Safety and lifecycle

Postmarket record

Recall and adverse-event records are shown only after product matching. Adverse-event reports do not establish incidence or causality.

Postmarket safety review
The wave22 exact-submission recall query returned no native recall record for K243038. This does not establish absence of family, later-version, or adverse-event information.
Public source Exact FDA submission Checked 2026-09-07

Buyer worksheet

Open questions to take to the vendor

Open evaluation checklist

Research record

What has been checked

This audit distinguishes completed source review from fields that have not yet been researched.

Human reviewedStatus
2026-09-07Last searched
24Fields reviewed
12Source classes checked
0Reviewed PubMed leads
0Reviewed trial leads
0Unreviewed FDA recall leads

The stored PubMed and ClinicalTrials.gov candidate arrays were screened and were empty. No paper or trial was promoted; empty stored arrays do not establish that no external literature or trials exist. The current discovery snapshot contains 0 PubMed and 0 ClinicalTrials.gov candidate records; its dated, count-matched human screening remains current. Unlinked candidates remain quarantined. Native FDA recall identifiers produced 0 postmarket candidate records; 0 have been reviewed (0 published, 0 rejected) and 0 remain unreviewed.

Candidate leads were screened against the exact product and tested version. Unlinked records remain quarantined.

Source classes: fda ai list, fda decision summary, acr ai central product, vendor product page, vendor regulatory page, fda device recall, literature index, trial registry, stored candidate metadata, pubmed, clinical trials, openfda device recall

Sources

Source ledger

Sources accessed through 2026-09-07.

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